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mRNA was extracted from the total RNA using poly-Toligo-attached magnetic beads ( Clustering and Sequencing The index-coded samples were clustered using the TruSeq PE Cluster Kit v3-cBot-HS (Illumina) on a cBot Cluster Generation System according to the manufacturers instructions

Notably, studies show that most LBD patients experience at least one NPS episode, with symptoms often fluctuating or recurring (Vik-Mo et al., 2020), while FTD also exhibits fluctuating NPS patterns, often prominent in both early and late stages (Morrow et al., 2024)